MBCP® is a synthetic bone graft substitute made of biphasic calcium phosphate: a mixture of hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP). It is used to fill or reconstruct bone defects and gaps that are not intrinsic to the stability of the bone structure, alone or with autograft.
The material has a global porosity of 70%, similar to cancellous bone, from an interconnected network of macropores and micropores. It is osteoconductive and resorbable: it gradually dissolves, releasing calcium and phosphate ions, and is replaced by new bone. MBCP is supplied as granules, sticks, blocks, wedges and cylinders, and as In’Oss™, a mouldable putty.
Features
- Fully synthetic biphasic calcium phosphate (HA/β-TCP).
- Two ratios: 60/40 and 20/80 HA/β-TCP (20/80 as granules only).
- 70% global porosity, with interconnected macropores and micropores.
- Osteoconductive and resorbable.
- Granules in vials or a mixing and delivery syringe, sticks, blocks, wedges and cylinders.
- In’Oss™ mouldable, injectable putty in syringes of 0.5 to 10 mL.
- Can be mixed with autograft, serum, whole blood or bone marrow aspirate.
- Supplied sterile; class III medical device.
Indications
A bone graft to fill or reconstruct bone defects or gaps of the skeletal system (for example extremities, spine and pelvis) that are not intrinsic to the stability of the bone structure. The defects may result from trauma or be surgically created.
MBCP can be used with autograft as a bone graft extender, and may be combined with the patient's own serum, whole blood or bone marrow aspirate.
See the instructions for use for contraindications, warnings and precautions.
Material
- Synthetic biphasic calcium phosphate: hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP).
- Two ratios: 60% HA / 40% β-TCP, and 20% HA / 80% β-TCP (granules only).
- Global porosity of 70%, similar to cancellous bone, from an interconnected network of macropores (over 100 µm) and micropores (under 10 µm).
- Osteoconductive and resorbable: the material gradually dissolves and is replaced by new bone. The resorption time depends on the size and site of the defect, the surgical protocol and the patient's health.
Forms
- Granules in vials (0.5–1.0, 1.0–2.0 and 2.0–3.0 mm) or in a mixing and delivery syringe (1.0–2.0 mm), which can be combined with bone marrow aspirate.
- Sticks and blocks, wedges (straight or rounded) and cylinders (8 to 14 mm diameter, 20 mm long).
- In'Oss™ putty: MBCP granules in a hydrogel, mouldable and injectable, in syringes of 0.5 to 10 mL. It keeps its shape in the graft site and is gradually replaced by bone.
- Custom-made shapes on request from the manufacturer.
Shelf life is 5 years for the solid forms and 3 years for In'Oss putty.
Sizes and ordering
All forms are supplied sterile; each pack holds one unit unless stated. Codes are from the manufacturer's 2024 MBCP Technology orthopaedics and trauma brochure (P1600 2024-03). Not all codes are available in every country: please confirm availability with Lavender Medical.
MBCP granules in vial11 items
| Ref. | Granule size | Volume |
|---|---|---|
| 1301G30 | 0.5–1.0 mm | 2 × 15 cm³ |
| 9902G02 | 1.0–2.0 mm | 2 cm³ |
| 0802G05 | 1.0–2.0 mm | 5 cm³ |
| 9902G10 | 1.0–2.0 mm | 10 cm³ |
| 0602G30 | 1.0–2.0 mm | 2 × 15 cm³ |
| 9903G02 | 2.0–3.0 mm | 2 cm³ |
| 0503G05 | 2.0–3.0 mm | 5 cm³ |
| 9903G10 | 2.0–3.0 mm | 10 cm³ |
| 9903G16 | 2.0–3.0 mm | 2 × 8 cm³ |
| 0803G20 | 2.0–3.0 mm | 2 × 10 cm³ |
| 0603G30 | 2.0–3.0 mm | 2 × 15 cm³ |
MBCP granules in syringe4 items
| Ref. | HA / β-TCP | Volume |
|---|---|---|
| 1102GS05 | 60 / 40 | 5 cm³ |
| 1102GS10 | 60 / 40 | 10 cm³ |
| 1502M+G05 | 20 / 80 | 5 cm³ |
| 1502M+G10 | 20 / 80 | 10 cm³ |
MBCP sticks and blocks9 items
| Ref. | Size | Per pack |
|---|---|---|
| 9801B02 | 5 × 5 × 10 mm | 2 |
| 9801B04 | 5 × 5 × 10 mm | 4 |
| 9802B02 | 5 × 5 × 20 mm | 2 |
| 9802B04 | 5 × 5 × 20 mm | 4 |
| 0810B01 | 10 × 10 × 10 mm | 1 |
| 0940B01 | 10 × 10 × 40 mm | 1 |
| 0850B01 | 10 × 20 × 50 mm | 1 |
| 0830B01 | 10 × 30 × 30 mm | 1 |
| 0825B01 | 12 × 25 × 25 mm | 1 |
MBCP wedges10 items
| Ref. | Wedge |
|---|---|
| 9905C01 | Straight, base 5 mm |
| 9906C01 | Straight, base 6 mm |
| 9908C01 | Straight, base 8 mm |
| 9910C01 | Straight, base 10 mm |
| 9912C01 | Straight, base 12 mm |
| 0106C01 | Rounded, 6 mm |
| 0108C01 | Rounded, 8 mm |
| 0110C01 | Rounded, 10 mm |
| 0112C01 | Rounded, 12 mm |
| 1414C01 | Rounded, 14 mm |
MBCP cylinders, 20 mm long5 items
| Ref. | Diameter |
|---|---|
| 0408D01 | 8 mm |
| 0409D01 | 9.5 mm |
| 0410D01 | 10 mm |
| 0412D01 | 12 mm |
| 0414D01 | 14 mm |
In'Oss putty (60% HA / 40% β-TCP in hydrogel)5 items
| Ref. | Syringe volume |
|---|---|
| 1004PU50OR | 0.5 mL |
| 1405PU01OR | 1.0 mL |
| 1105PU025OR | 2.5 mL |
| 1106PU05OR | 5.0 mL |
| 1107PU010OR | 10.0 mL |
Codes and sizes are taken from the manufacturer's marketing literature and may change. For current information, check the Biomatlante website or the instructions for use before ordering.
Product information
What is MBCP made of?
Biphasic calcium phosphate, a mixture of hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP). It is fully synthetic.
Which ratios are available?
60% HA / 40% β-TCP in all forms, and 20% HA / 80% β-TCP as granules only.
What can it be mixed with?
Autograft, as a bone graft extender, or the patient's own serum, whole blood or bone marrow aspirate.
What is In'Oss?
A mouldable, injectable putty made of MBCP granules (60% HA / 40% β-TCP) in a hydrogel, supplied in syringes of 0.5 to 10 mL.
What is the shelf life?
5 years for the solid forms and 3 years for In'Oss putty.
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